Ostrich connected via a USB port, Nissan Data Scan connected to another USB port and my wideband connected to the serial port. It is a little more difficult to find the exact map cell to edit but it isn't too bad. The ECU averages 4 adjacent cells to determine the correct value so cells usually get edited in groups rather than individually anyway.
The Ostrich is a reliable tool that is less expensive than Nistune. Nistune runs close to $600 US with hardware and software license. Ostrich was $175. I used the difference to buy an LM-1 wideband.