The OS in installed on a locked SD card. When I mean locked, nothing is written to the drive after my install. So, when loading windows, its almost like a fresh install of XP. I dont have to worry about read/writes to the SD card. My videos/audio files are on the HD but can be a easy replace as I have it all on another HD in the house.
This is not my first install, and my last installed HD lasted over 4 years. (worked fine even after the pull) No this is nothing to worry about.